The Effect of DNA Phase Structure on DNA Walk
S. Cebrat1, M.R. Dudek2
1 Institute of Microbiology, University of Wrocaw, ul.
Przybyszewskiego 63/77, 51-148 Wrocaw, Poland
2 Institute of Theoretical Physics, University of Wrocaw, pl. Borna 9,
50-204 Wrocaw, Poland
European Physical Journal,
B3:271-276 (1998)
Abstract
We have performed several kinds of DNA walks which often are the first
steps for further analysis of DNA structure and long range correlations.
The DNA walks analysing frequency of G+C versus A+T cannot indicate
the coding strand while purine versus pyrimidine DNA walks or
two-dimensional (A-T,G-C) DNA walks in some instances can indicate
the coding strand but cannot resolve the coding frame. The modified
two-dimensional (A-T,G-C) DNA walks respecting the three-nucleotide
codon structure show very high correlation in nucleotide composition of
DNA coding sequences. They can distinguish between coding and
non-coding sequences and indicate the strand and the phase in which
DNA is coding.
