Redundancy of Eukaryotic DNA Decreases After Excision of Introns

T.G. Popova and M.G. Sadovskii

Molecular Biology 29(3), 281--285 (1995)

Abstract

The article is devoted to analysis of the internal gene structure with respect to redundancy of exons and introns. Human genes with precisely determined exon-intron structure were studied. Redundancy of each exon and intron within a certain gene was measured. In the analyzed human genes, introns were more redundant than exons. Redundancy was determined as the minimal length of a word (oligonucleotide) that is present as a single copy within the nucletide sequence studied. Mechanisms are discussed that lead to disturbances in the relationships found between the redundancies of exons and introns.