Patchiness and correlations in DNA sequences
Samual Karlin, Volker Brendel
Science 259, 677--680 (January 29, 1993)
Abstract
The highly nonrandom character of genomic DNA can confound attempts
at modeling DNA sequence variation by standard stochastic processes
(including random walk or fractal models). In particular, the mosaic
character of DNA consisting of patches of different compositional
can fully account for apparent long-range correlations in DNA.