Recognition of Protein Coding Regions in DNA Sequences
James W. Fickett
Nucleic Acids Research, 10(17):5303-5318 (1982)
Abstract
We give a test for protein coding regions which is based on simple
and universal differences between protein-coding and noncoding DNA.
The test is simple enough to use without a computer and is completely
objective. The test has been thoroughly proven on 400,000 bases
of sequence data: it misclassifies 5% of the regions tested and gives
an answer of "No Opinion" one fifth of the time. We predict some new
coding and noncoding regions in published sequences.
