Statistical Analysis of Mammalian Pre-mRNA Splicing Sites
M.S. Gelfand
Nucleic Acids Research, 17(15):6369-6382 (Aug 11, 1989)
Abstract
222 donor and 222 acceptor (including 206 pairs) non-homologous
splicing sites were studied. Well known features of these were
confirmed and some novel observations were made. It is (1) cCAGGGag
signal in (-60)-(-58) region of acceptor sites; (2) strong
complementarity between regions (-69)-(-55) and (-36)-(-22) of some
of the acceptor sites, and (3) small but statistically significant
correlation between discrimination energies of corresponding donor
and acceptor sites.
