genehunter man page (version 1.1, dec 1996)


DISCARD

Summary: eliminate less informative individuals
Argument: < 'on' or 'off' >
Default: displays the current setting

As noted in the "scan" command, some larger pedigrees can be quite time consuming to analyze. To speed this up, some less informative individuals can be discarded without significant loss of information. When the "discard" option is turned on, unaffected individuals that have no descendents in the pedigree and have informative parents (i.e, genotyped) are discarded from analysis. This will alter results somewhat (LOD scores more than NPL statistics since the unaffected individuals are not considered in NPL statistics which measure the degree of sharing among affected individuals) and should only be used if you are interested in obtaining a fast approximation of the results or if your pedigrees are extremely large and cannot be fully analyzed by GENEHUNTER.