course annoucement: http://www.icgeb.trieste.it/MEETINGS/CRS05/Meetings2005.htm
| March 9 (Wed) | March 10 (Thu) | March 11 (Fri) | |
| 9-11:30am |
W1
Introduction to population genetics
Dr. Hector Rangel |
T1
Practical issues in association analysis.
I. indirect nature of disease genes
[click here]
Dr. Wentian Li |
F1
Various statistical issues in association analysis.
[click here]
Dr. Wentian Li |
| 11:30-12am | coffee break | coffee break | coffee break |
| 12-14pm |
W2
Basic programs for descriptive population
genetics Dr. Hector Rangel |
T2 exercise |
F2
exercise and self-learning
[click here]
Dr. Hector Rangel, Dr. Wentian Li, Alejandro Morales |
| 14-15:30pm | lunch | lunch | END OF COURSE |
| 15:30-17pm |
W3
Introduction to association analysis
[click here]
Dr. Wentian Li |
T3
Practical issues in association analysis.
II. heterogeneity
[click here]
Dr. Wentian Li exercise and self-learning [click here] Dr. Hector Rangel, Dr. Wentian Li, Alejandro Morales |
|
| 17-17:15pm | coffee break | coffee break | |
| 17:15-19pm |
W4
exercise and self-learning
[click here]
Dr. Hector Rangel, Dr. Wentian Li, Alejandro Morales |
T4
Family-based association analysis,
interactions, and other topics
[click here]
Dr. Wentian Li |
-Introduction to association studies W3
-Causes of association (population causes and genetic causes)
T2, T4
- Interpretation of association Linkage disequilibrium
T1
- Case-control studies using population controls for detecting association
W3
- Analytical issues (e.g. dealing with highly polymorphic markers)
?
- Issues regarding the study design (e.g. the problem of population
stratification)
T2
- Association studies using family-based controls
T2, T4
- Methods based on parental transmissions to affected child (haplotype
relative risk and transmission/disequilibrium test)
T2, T4
- Methods using a variety of relatives as controls (v.g. unaffected
siblings)
T4
- Analysis issues (multiple alleles, likelihood-based approaches)
F1
- Power of population-based and family-based methods
F1
- Gene-environment interactions, power and study design
T2, T4
- Approach of whole genome screens
F1
- Comparing between linkage or association studies
T4
- Power of association studies Isolated populations and its application to
complex diseases analysis
T2