Wentian Li, Ph.D
Associate Investigator
The Robert S. Boas Center for Genomics and Human Genetics
Feinstein Institute for Medical Research
North Shore LIJ Health System

home page
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genetic association
copy number variations
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Other resources
100 human genes
2005 Mexico course on genetic association analysis
Perl code for recursive segmentation of DNA sequences
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EDUCATION
---------

 Jan 1982. B.A.  Physics Department, Beijing University, Beijing, China
 Jun 1984. M.A.  Physics Department, Columbia University, New York, NY
 Oct 1989. Ph.D  Physics Department, Columbia University, New York, NY
 	         Ph.D Thesis: "Problems in Complex Systems"
		 Thesis advisors: Dr. Stephen Wolfram (founder of
		 Wolfram Research Inc. and the author of Mathematica),
		 Dr. Norman Packard (co-founder of Prediction Company).

EMPLOYMENTS
-----------

 1982-1984, Teaching assistant, Physics Department, Columbia University.
 1984-1985, Thesis contract student, Theoretical condensed matter physics
	 group, Brookhaven National Lab.
 1986 spring, Teaching assistant, Physics Department, Columbia University.
 1986-1989, Founding staff member, Center for Complex Systems Research,
	University of Illinois at Urbana-Champaign.
 1989-1991, Collaborator, Center for Nonlinear Studies, Los Alamos National
	Lab.
 1989-1991, Postdoctoral Fellow, Santa Fe Institute.
 1991-1992, Postdoc, Statistical Physics Lab, Rockefeller University.
 1992-1994, Postdoc, Computational Molecular Biology Group, Cold Spring
	Harbor Lab.
 1995-1996, Research Scientist, Statistical Genetics Department, New York
	State Psychiatric Institute,
 1995-1996, Associate Research Scientist, Psychiatric Department,
	Columbia University
 1996-1997, Research Associate, Statistical Genetics Lab, Rockefeller
	University
 1997-2001, Assistant Professor, Statistical Genetics Lab, Rockefeller
        University
 2001-2007, Research Scientist, The Robert S Boas Center for Genomics and Human Genetics,
	Feinstein Institute for Medical Research, North Shore LIJ Health System
 2008-now, Associate Investigator, The Robert S Boas Center for Genomics and Human Genetics,
        Feinstein Institute for Medical Research, North Shore LIJ Health System
 2008-now, Associate Professor, Elmezzi Graduate School of Molecular Medicine
        Feinstein Institute for Medical Research, North Shore LIJ Health System
 2008-now, Associate Professor, Department of Epidemiology and Population Health ,
 	Albert Einstein College of Medicine

HONORS/AWARDS
-------------

 1981: CUSPEA Fellowship (CUSPEA, or China-US Physics Examination and
	Application, is a program organized by Nobel Laureate T.D. Lee which
	annually admits about 100 Chinese physics students nation-wide to
	study in US).
 1982-1983: Faculty Fellow, Columbia University
 1989-1991: Postdoctoral Fellow, Santa Fe Institute
 1997-2001: Special Emphasis Research Career Award (SERCA) in Genome
        Research, National Human Genome Research Institute, National
        Institute of Health.
 1997: Nominee of the James McDonnell Centennial Fellowship (nominated
	by Rockefeller University)

FUNDINGS - ONGOING
-------------------

 NIH/NIAID 09/2005-02/2010, PI: Steve Hauser, co-PI: Peter Gregersen
 "International MHC Genetics Network (Imagen)" (U19)

 NIH/NIAMS 04/2008-03/2011, PI: Lou Bridges
 "Predictors of Rheumatoid Arthritis (RA) Severity in African Americans" (subcontract)

 NIH/NIAMS 04/2007-03/2012, PI: Peter Gregersen
 "The Genetics of Rheumatoid Arthritis -NARAC" (RO1 AR44422)

 NIH/NIAID 07/2007-06/2012, PI: Peter Gregersen
 "Mapping Autoimmune Phenotypes in Multiplex families" (RO1-AI-68759)

FUNDINGS - COMPLETED
-------------------

 NIH/NHGRI, 4/30/1997 - 4/30/2001, $325,432, PI: Wentian Li
 "Training in Genomic Research for Complex Diseases",

 NIH/NIAMS 08/1997-07/2008, PI: Peter Gregersen
 "Genetics Of Rheumatoid Arthritis" (NO1-AR-2-2263)

 NIH/NIAMS 10/2001-09/2008, PI: Peter Gregersen
 "Autoimmune Biomarkers Collaborative Network (ABCoN)" (NO1-AR-1-2256)

 NIH/NIAMS, 06/2002-05/2006, PI: Peter Gregersen
 "Genetic analysis of rheumatoid arthritis sib pairs" (R01 AR44422)


PROFESSIONAL ACTIVITIES - JOURNAL EDITOR
----------------------------------------

 Guest Editor: Gene (2002)
 Editorial Board Member: Computational Biology and Chemistry (2003 - now)
 Editorial Board Member: Journal of Theoretical Biology (2005- now)
 Editorial Board Member: Bioinformatics (2005- 2008)
 Review Editor: Frontier in Fractal Physiology (2010-now)


PROFESSIONAL ACTIVITIES - MANUSCRIPT REVIEWER
---------------------------------------------

 (total 86 journals. if name changes of the same journal are discounted, then 84 journals)

 Advances in Complex Systems (1999,2001,2003,2006-2times,2007)
 American Journal of Epidemiology (2006)
 American Journal of Medical Genetics (2003)
 American Journal of Human Genetics(2002,2004,2007)
 Applied Bioinformatics (2001,2003,2004-2times)
 Artificial Intelligence in Medicine (2008)
 Artificial Life (2001)
 Arthritis & Rheumatism (2004-4times)
 BioEssays (2003)
 Bioinformatics (2001-2times,2002-4times,2004,2005-4times,2006-2times,
2007-5times,2008-2times,2009,2010, 2011)
 Biomarker Insights (2007)
 Biophysical Chemistry (2000)
 Biophysical Journal (1996)
 Biotechniques (2001)
 BMC Bioinformatics (2002,2005-3times,2006-2times,2007,2009)
 BMC Evolutionary Biology (2008)
 BMC Genetics (2004,2005)
 BMC Genomics (2009)
 BMC Medical Genetics (2006)
 BMC Medical Genomics (2010)
 BMC Proceedings(2007-2times, 2008-2times, 2009-2times,2011)
 Cell Biochemistry and Biophysics (2002,2003)
 Chaos (1992)
 Comparative and Functional Genomics (2007)
 Complexity (1997,98,2000,2001)
 Complex Systems (1993,2000,2001,2007)
 Computational Biology and Chemistry (2002,2003-6times,2004-9times,2005-4times,2006-2times,
2007,2009-6times,2010-5times,2011-3times)
 Computer Applications in Biosciences (1996-3times,97)
 Computers and Chemistry (bioinformatics special issue) (1993,1999,2000)
 Entropy (2011)
 EURASIP Journal on Applied Signal Processing (2003-2times)
 EURASIP Journal on Bioinformatics and System Biology (2006)
 European Physical Journal (2002,2011)
 Europhysics Letters (1993,2005)
 FEBS Letters (2004,2005)
 Frontiers in Fractal Physiology (2010)
 Gene (2001,2002-4times,2003,2004,2006-2times)
 Gene and Immunity (2008)
 Genetics (2009)
 Genome Biology (2002)
 Genome Biology and Evolution (2011)
 Genomics (1996,2001,2003,2008)
 Genome Research (1999,2001-2times,2004)
 Human Genetics (2008-2times)
 Human Heredity (1999,2002)
 IEEE Signal Processing Letters (2005)
 IEEE Transactions on Computational Biology and Bioinformatics (2004,2005)
 IEEE Transactions on Systems, Man and Cybernetics (1998)
 Indian Journal of Biochemistry and Biophysics (2011)
 Information Retrieval (2003)
 International Journal of Artificial Intelligence in Medicine (2003)
 International Journal of Bioinformatics Research and Applications (2009)
 International Journal of Natural Computing Research (2010)
 Journal of American Society for Information Science and Technology (2008)
 Journal of Bioinformatics and Computational Biology (2003,2004,2007)
 Journal of Biomolecular Structure and Dynamics (2003,2005,2007-2times)
 Journal of Chemical Information and Computer Sciences (2004)
 Journal of Computational Biology (2011)
 Journal of Evolutionary Biology Research (2011)
 Journal of Molecular Evolution (1997,2003-2times)
 Journal of Physics: Condensed Matter (2004)
 Journal of the Royal Society Interface (2007)
 Journal of Statistical Physics (1999)
 Journal of Theoretical Biology (1998-2times,2000,2001,2003,2004-4times,2006,2008-2times,2009,2011)
 Mammalian Genome (2003)
 Mathematical Biosciences (2002)
 Metabolic Engineering (1999)
 Molecular Biology and Evolution (2010)
 Molecular Genetics and Metabolism (2004)
 Molecular Medicine (2006,2007,2008-2times,2009)
 Nature (1992)
 Nucleic Acids Research (1998,2001,2002-2times,2004,2005-2times,2006)
 Physica A (2004,2005,2007,2010,2011)
 Physica D (1990,1991,94,99,2002-2times,2008)
 Physical Biology (2009-2times)
 Physical Review E (1997-3times,98-3times,99-3times,2000-2times,2001-3times,
  2002-4times,2003-2times,2004-4times,2005,2006-2times,2007,2008,2009-3times,
  2010-2times, 2011-3times)
 Physical Review Letters (1996,97-2times,98,99-3times,2000-2times,2001-3times,
  2002, 2003-2times,2004-2times,2005-2times,2006,2008-2times)
 Physics Letters A (1991)
 PLoS Computational Biology (2006)
 PLoS One (2009)
 Proceedings of National Academy of Sciences (2006)
 Revista Mexicana de Fisica (2009)
 Seminars in Arthritis and Rheumatism (2007)
 Statistical Applications in Genetics and Molecular Biology (2010)
 Statistics in Medicine (2010)
 Theory in Biociences (2006)


 Pacific Symposium on Biocomputing (2003)
 Research in Computational Biology (RECOMB) (2003)
 IEEE/EMBS Annual Conference (2006)
 Asia-Pacific Bioinformatics Conference (2007-9times, 2009-8times, 2010-6times 
[handling 13 submissions], 2011-2times [handling 9 submissions])
 Advances in Computational Intelligence in Bioinformatics (2007)


PROFESSIONAL ACTIVITIES - GRANT REVIEW
---------------------------------------

 Action Thematique Incitative sur Programme et Equipes (ATIPE),
 Centre National de la Recherche Scientifique (CNRS), France (2000).

 David Phillips Fellowship, Biotechnology and Biological Sciences Research
 Council (BBSRC), UK (2005).

 Wellcome Trust, UK (2006-twice)

 Department of Biotechnology, Ministry of Science and Technology, India (2006)

 Wellcome Trust, UK (2007)
 
 National Institute of Health, USA (2011): TMEN, NCI special emphasis panel


PROFESSIONAL ACTIVITIES - MEETING CHAIRS
----------------------------------------

 IEEE Engineering in Medicine and Biology Society (EMBS) Annual International
 Conference: track co-chair for Bioinformatics and Computational Biology (2006)

 Asia-Pacific Bioinformatics Conference (APBC'2007): program committee

 Asia-Pacific Bioinformatics Conference (APBC'2009): program committee

 Asia-Pacific Bioinformatics Conference (APBC'2010): program committee

 Asia-Pacific Bioinformatics Conference (APBC'2011): program committee

 Genome Informatics Workshop (GIW'11): program committee.


PROFESSIONAL ACTIVITIES - COMMITTEE
-----------------------------------

 Scientific Committee, Critical Assessment of Microarray Data Analysis
 (CAMDA) Workshop, October 2001

 Academic Medicine Development Company (AMDEC) Bioinformatics Core Advisory
 Committee (2001- 2002).


PROFESSIONAL ACTIVITIES - TRAINING
----------------------------------

 Complex Systems Summer School (Santa Fe Institute, June/July 1988).

 SIMS Tutorial:  Mathematical Sciences in Genomic Analysis (sponsored
 by Societal Institute of the Mathematical Sciences, at Rutgers
 University,  July/August, 1992).

 Training Course for IntelliGenetics Suite (given by IntelliGenetics Inc.,
 at Cold Spring Harbor Lab, December 1993).

 Advanced Linkage Course (Columbia-Presbyterian Medical Center,
 Columbia University, January 1994).

 1994 Princeton Biophysics Lectures (NEC Institute, June 1994 and
 June 1992).

 Genetic Epidemiologic Studies of Complex Diseases (auditing, Banbury
 Center, Cold Spring Harbor Lab, June 1994).

 Theoretical Genetic Modeling Course (auditing, Department of
 Biostatistics, Columbia University, Spring, 1996).

 Genetic approaches to biological problems(auditing, Genetics and
 Development Department, Columbia University, Fall, 1997).

 Quantitative genetic data analysis(Statistics Department,
 North Carolina State University, June 1998).

 Human Disease Mapping (Statistics Department, North Carolina
 State University, June 1999).



PROFESSIONAL ACTIVITIES - RECENT CONFERENCE PRESENTATIONS
---------------------------------------------------------

 Annual Meeting of American Society of Human Genetics (1995,96,97,98,99,2000).
 Anton Dohrn Workshop on Natural Selection and Neutral Theory (2001, 2005).
 Aspen Workshop on Identifying Features in Biological Sequences (1990,93,96).
 Beijing Computational Biology Workshop (1999).
 Chinese Bioinformatics Conference (2002).
 Critical Assessment of Techniques for Microarray Data Mining (2000).
 Cold Spring Harbor Genome Meeting (1994,98,99,2000).
 Cold Spring Harbor Genome Sequence, Sequence Variation, and Gene Expression
   Meeting (2001)
 Institute of Mathematics and Applications (IMA) workshop on Statistical
   Methods for Gene Expression (2003)
 DNA in Chromatin (2002)
 Gene Discovery in silico (1997).
 Genetic Analysis Workshop (1996,98,2000).
 Research in Computational Molecular Biology (RECOMB) (1998,2001,2003).


PROFESSIONAL ACTIVITIES - SUPERVISING STUDENTS/EDUCATION
--------------------------------------------------------

 David Kessler, pre-college science education program at Rockefeller
 University (1998,99,2000 summers) (an undergraduate at Harvard University
 (2000-2004) major: economics ).

 Eric van Nostrand, pre-college science education program at Rockefeller
 University (2000 summer).  (an undergraduate at MIT (2001-2005) major: biology;
 graduate student at Stanford University (2006-) )

 Young-Ju Suh, outside committee member for Ph.D Thesis, Dept of Applied
 Mathematics and Statistics, State Univ of New York at Stony Brook (2001).
 (currently a researcher at Samsung Biomedical Research Institute)

 Lecture: pre Chinese Bioinformatics Conference Course (2002). Institute of
 Theoretical Physics, Chinese Academy of Sciences, Beijing.
 "Introduction of microarray data analysis".

 Lecturer and organizing committee: Theoretical and Practical Course: Pharmacogenomics
 - genetic epidemiology and web-based tools (2005). Guadalajara, Mexico.
 "Introduction to association analysis",
 "Practical issues in association analysis. I. indirect nature of disease genes",
 "Practical issues in association analysis. II. heterogeneity",
 "Family-based association analysis, interaction, and other topics",
 "Various statistical issues in association analysis".

 Sharon Chou, high-school summer student (2002) (an undergraduate at MIT (2004-2008)
 major: EECS).

 Ken Asher, Student Intern Research Program at Feinstein Institute for
 Medical Research (2006, 2007) (an undergraduate at SUNY Stony Brook (2008-)
 major: mathematics).

 Lecture: Graduate Course on Genetics (2007), North Shore LIJ Graduate School of
 Molecular Medicine
 "Introduction of model-based linkage analysis"

 Lisa Mao, college summer student (2007)

 Ayesha Hameed, college summer student (2008)

 Zafar Zaheer, Ph.D Thesis evaluation, University of Peshawar (2009)

 Lecture: Graduate Course on Genetics (2010), Elmezzi Graduate School of 
 Molecular Medicine
 "Introduction of genetic linkage analysis"

 Lecture: Graduate Course on Genetics (2010), Elmezzi Graduate School of 
 Molecular Medicine
 "Testing genetic association between a marker and the disease in case-control studies"


COMPUTER EXPERIENCES
--------------------

 Programming: C (since 1986), Perl (since 1995), and others.
 Web: webmaster (since 1995).
 System administration: full-time UNIX administrator (1995-96).
 Scientific programming: S-plus (since 1998), Mathematica (since 1989),
   and others.



PUBLICATIONS - JOURNAL ARTICLES, LETTERS, EDITORIAL
---------------------------------------------------

 (58 papers are first-author'ed)
 (total citations: at least 2000 as of July 2009)

103. W Li (2012),
 "Menzerath's law at the gene-exon level in the human genome",
 Complexity, to appear.

102.  E Prado Montes de Oca, W Li  (2012), 
 "Human beta-defensin 1 (DEFB1) alleles and genotypes frequencies probably impacts 
 atopic dermatitis ethnic susceptibility" (correspondence), 
 International Journal of Dermatology, to appear.

101. W Li (2012),
 "Fitting Chinese syllable-to-character mapping spectrum by the beta rank function", 
 Physica A, 391:1515-1518.

100. C Calissano, RN Damle, S Marsilio, XJ Yan, S Yancopoulos, G Hayes, C Emson, 
EJ Murphy, MK Hellerstein, C Sison, MS Kaufman, JE Kolitz, SL Allen, KR Rai, 
I Ivanovic, IM Dozmorov, S Roa, MD Scharff, W Li, N Chiorazzi (2011),
 "Intra-clonal complexity in chronic lymphocytic leukemia: 
 fractions enriched in recently born/divided and older/quiescent cells",
 Molecular Medicine, 17:1374-1382.

99.  XJ Yan, I Dozmorov,  W Li, S Yancopoulos, C Sison, M Centola,  
 P Jain, SL Allen, JE Kolitz, KR Rai, N Chiorazzi, B Sherry (2011),
 "Identification of outcome-correlated cytokine clusters in chronic
 lymphocytic leukemia",
 Blood, 118:5201-5210.

98. W Li (2011),
 "On parameters of the human genome",
 Journal of Theoretical Biology, 288(7):92-104.

97. M Brenner, CP Linge,  W Li, PS Gulko (2011),
 "Increased synovial expression of nuclear receptors correlates 
 with arthritis protection: a possible novel mechanism of articular 
 homeostasis (regulated by Cia25)",
 Arthritis & Rheumatism, 63(10):2918-2929.
 
96. W Li, P Miramontes (2011), "Fitting ranked English and Spanish letter 
 frequency distribution in U.S. and Mexican presidential speeches", 
 Journal of Quantitative Linguistics, 18(4):337-358. 

95. Y Yang, E Remmers, C Ogunwole, D Kastner, PK Gregersen, W Li (2011),
 "Effective sample size: quick estimation of the effect of relative pairs
 in genetic case-control association analyses",
 Computational Biology and Chemistry, 35(1):40-49.

94. W Li, C He, J Freudenberg (2011),
 "A mathematical framework for examining whether a minimum number of
 chiasmata is required per metacentric chromosome or chromosome arm in human",
 Genomics, 97(3):186-192.

93. J Freudenberg, AT Lee, KA Siminovitch, CI Amos, D Ballard, W Li, PK Gregersen (2010),
 "Locus category based analysis of a large genome-wide-association study of rheumatoid arthritis",
 Human Molecular Genetics, 19(19):3863-3872.

92. W Li, P Miramontes, G Cocho (2010),
 "Fitting ranked linguistic data with two-parameter functions",
 Entropy, 12(7):1743-1764.

91. W Li, J Freudenberg (2009),
 "Two-parameter characterization of chromosome-scale recombination rate",
 Genome Research, 19:2300-2307.

90. T Seiler, M Woelfle, S Yancopoulos, R Catera, W Li, K Hatzi, C Moreno,
 M Torres, S Paul, H Dohner, S Stilgenbauer, MS Kaufman, JE Kolitz, SL Allen,
 KR Rai, CC Chu, N Chiorazzi (2009),
 "Characterization of structurally-defined epitopes recognized by monoclonal antibodies
 produced by chronic lymphocytic leukemia B cells",
 Blood, 114(17):3615-3624.

89. W Li, Y Yang (2009),
 "Fractal characterizations of MAX statistical distribution  in genetic
 association studies",
 Advances in Complex Systems, 12(4-5):513-531.

88. JL Santiago, W Li, A Lee, A Martinez, A Chandrasekaran, M Fernandez-Arquero,
 H Khalili, EG de la Concha, E Urcelay, PK Gregersen (2009),
 "Localization of Type 1 Diabetes susceptibility in the Ancestral Haplotype 18.2 by high
 density SNP mapping",
 Genomics, 94(4):228-232.

87.  W. Hueber, B.H. Tomooka, F. Batliwalla, W Li, P.A. Monach, R.J. Tibshirani,
 R.F. Van Vollenhoven, J. Lampa, K. Saito, Y. Tanaka, M.C. Genovese, L. Klareskog,
 P.K. Gregersen, W.H. Robinson (2009),
 "Blood autoantibody and cytokine profiles predict response to anti-tumor
 necrosis factor therapy in rheumatoid arthritis",
 Arthritis Research & Therapy, 11(3):R76.

86. W Li, A Lee, PK Gregersen (2009)
 "Copy-number-variation and copy-number-alteration region detection by cumulative plots",
 BMC Bioinformatics, 10(suppl 1):S67.

85. J Freudenberg, M Wang, Y Yang, W Li (2009)
 "Partial correlation analysis indicates causal relationships between
 GC-content, exon density and recombination rate variation in the human genome",
 BMC Bioinformatics, 10(suppl 1):S66.

84.  T Laragione, M Brenner, W Li, PS Gulko (2008)
 "Cia5d regulates a new fibroblast-like synoviocyte invasion-associated
 gene expression signature",
 Arthritis Research & Therapy, 10:R92.

83. W Li, YJ Suh, Y Yang (2008)
 "Exploring case-control  genetic association tests using phase diagrams",
 Computational Biology and Chemistry, 32(6):391-399.

82. C Liu, F Batliwalla, W Li, A Lee, R Roubenoff, E Beckman, H Khalili,
 A Damle, M Kern, R Furie, RM Plenge, M Coenen, TW Behrens, JP Carulli,
 PK Gregersen (2008),
 "Genome-wide association scan identifies candidate polymorphisms associated
 with differential response to anti-TNF treatment in rheumatoid arthritis",
 Molecular Medicine,  14:575-581.

81. G Zheng, M Meyer, W Li, Y Yang (2008),
 "Comparison of two-phase analyses for case-control genetic association studies"
 Statistics in Medicine, 24:5054-5075.

80. HS Lee, AT Lee, LA Criswell, MF Seldin, CI Amos, JP Carulli,
 C Navarrete, EF Remmers, DL Kastner, RM Plenge, W Li, PK Gregersen (2008),
 "Several regions in the major histocompatibility complex confer risk for
 anti-CCP-antibody positive rheumatoid arthritis, independent of the DRB1 locus"
 Molecular Medicine, 14:293-300.

79. W Li (2008),
 "Three lectures on case-control genetic association analysis",
 Briefings in Bioinformatics, 9:1-13.

78. RM Plenge, M Seielstad, L Padyukov, AT Lee, EF Remmers, B Ding, A Liew,
 H Khalili, A Chandrasekaran, LRL Davies, W Li, AKS Tan, C Bonnard, RTH Ong,
 A Thalamuthu, S Pettersson, C Liu, C Tian, WV Chen, JP Carulli, D Altschuler,
 L Alfredsson, LA Criswell, CI Amos, MF Seldin, DL Kastner, L Lareskog,
 PK Gregersen (2007),
 "TRAF1-C5 as a risk locus for rheumatoid arthritis -- a genomewide study",
 New England Journal of Medicine, 357(12):1199-1209.

77. EF Remmers, RM Plenge, AT Lee, RR Graham, G Hom, TW Behrens, PIW de Bakker,
 JM Le, HS Lee, F Batliwalla, W Li, SL Masters, MG Booty, JP Carulli,
 L Padyukov, L Alfredsson, L Klareskog, WV Chen, CI Amos, LA Criswell,
 MF Seldin, DL Kastner, PK Gregersen (2007),
 "STAT4 and risk of rheumatoid arthritis and systemic lupus erythematosus",
 New England Journal of Medicine, 357(10):977-986.

76. YJ Suh, HS Lee, F Batliwalla, W Li (2007),
 "A comparison of founder-only and all-pedigree-members genotype-expression
 association by regression analysis",
 BMC Proceedings, 1(suppl 1):S8.

75.  YJ Suh, W Li (2007)
 "Genotype-based case-control analysis, violation of Hardy-Weinberg
 equilibrium, and phase diagram",
 Proceedings of the 5th Asia-Pacific Bioinformatics Conference,
 pp.185-194 (Imperial College Press).

74. PK Gregersen, E Kowalsky, W Li (2007)
 "Reply to Henthorn and Deutsch -- Ethnicity versus early environment:
 Comment on 'Early childhood music education and predisposition to absolute
 pitch: teasing apart genes and environment" (letters to the editor),
 American Journal of Medical Genetics, 143A:104-105.

73.  W Fury, F Batliwalla, PK Gregersen, W Li (2006),
 "Overlapping probabilities of top ranking gene lists, hypergeometric
 distribution, and stringency of gene selection criterion",
 Conference proceedings of Annual International Conference of the
 IEEE Engineering in Medicine and Biology Society, pp. 5531-5541 (IEEE).

72. JW Bauer, EC Baechler, M Petri,  FM Batliwalla, D Crawford, WA Ortmann,
 KJ Espe, W Li, DD Patel,  PK Gregersen , TW Behrens (2006),
 "Elevated serum levels of interferon-regulated chemokines are biomarkers for
 active human systemic lupus erythematosus",
 PLoS Medicine, 3(12):e491.

71.  HS Lee, W Li, A Lee, P Rodine, RR Graham, WA Ortmann, F Batliwalla,
 KW Lee, SC Bae, TW Behrens,  PK Gregersen (2006),
 "Microsatellite typing for DRB1 alleles: application to the analysis of
 HLA associations with rheumatoid arthritis",
 Gene and Immunity, 7:533-543.

70.  W Li, P Miramontes (2006),
 "Large-scale oscillation of structure-related DNA sequence features
 in human chromosome 21",
 Physical Review E, 74:021912.

69.  CI Amos, WV Chen, AT Lee, W Li, M Kern,  R Lundsten, F Batliwalla,
 M Wener, E Remmers, DA Kastner, LA Criswell, MF Seldin, PK Gregersen (2006),
 "High-density SNP analysis of 642 caucasian families with rheumatoid
 arthritis identifies two new linkage regions on 11p12 and 2q33",
 Gene and Immunity, 7(4):277-286.

68. E Shi, W Fury, W Li, W Mikulka, T Aldrich, A Rafique, G Chen,
 S Hoffenberg, TJ Daly, C Radziejewski (2006)
 "Monoclonal antibody classification based on epitope binding using
 differential antigen disruption",
 Journal of Immunological Methods, 314:9-20.

67. W Li (2006)
 "The-more-the-better and the-less-the-better",
 Bioinformatics, 22(18):2187-2188.

66. M Brenner, T Laragione, NC Yarlett, W Li, A Mello, PS Gulko (2006)
 "Cia27 is a novel non-MHC arthritis severity locus on rat
 chromosome 10 syntenic to the rheumatoid arthritis 17q22-q25 locus",
 Gene and Immunity, 7(5):335-341.

65. W Li, M Wang, P Irigoyen, PK gregersen (2006),
 "Inferring causal relationships among intermediate phenotypes and
 biomarkers: a case study of rheumatoid arthritis",
 Bioinformatics, 22(12):1503-1507.

64. FM Batliwalla, W Li, CT Ritchlin, X Xiao, M Brenner, T Laragione,
 T Shao, R Durham, S Kemshetti, E Schwarz, R Coe, M Kern, EC Baechler,
 TW Behrens, PK Gregersen, PS Gulko (2005),
 "Microarray analyses of peripheral blood cells identifies
 unique expression signature in psoriatic arthritis",
 Molecular Medicine, 11(1-12):21-29.

63. A Ulgen, W Li (2005),
 "Comparing single-nucleotide-polymorphism marker-based and
 microsatellite marker-based linkage analyses"
 BMC Genetics, 6(suppl 1):S13.

62. P Irigoyen, AT Lee, MH Wener, W Li, M Kern, F Batliwalla, RF Lum,
 E Massarotti, M Weisman, C Bombardier, EF Remmers, DL Kastner,
 MF Seldin, LA Criswell, PK Gregersen (2005),
 "Regulation of anti-cyclic citrullinated peptide antibodies
 in rheumatoid arthritis: contrasting effects of HLA-DR3 and
 the shared epitope alleles",
 Arthritis & Rheumatism, 52(12):3813-3818.

61. FB Batliwalla, EC Baechler, X Xiao, W Li, S Balasubramaniuan,
 H Khalili, A Damle, WA Ortmann, A Perrone, AB Kantor, PS Gulko,
 M Kern, R Furie, TW Behrens, PK Gregersen (2005),
 "Peripheral blood gene expression profiling in rheumatoid arthritis",
 Gene and Immunity, 6(5):388-397.

60. W Li, D Holste (2005),
 "Universal 1/f noise, crossovers of scaling exponents, and
 chromosome-specific patterns of guanine-cytosine content in
 DNA sequences of the human genome",
 Physical Review E, 71:041910.

59. LA Criswell, K Pfeiffer, RF Lum, B Gonzales, J Novitzke,
 M Kern, KL Moser, AB Begovich, VEH Carlton, W Li, AT Lee,
 W Ortmann, TW Behrens, PK Gregersen (2005),
 "Analysis of families in the Multiple Autoimmune Disease Genetics
 Consortium (MADGC): the PTPN22 620W allele associates with multiple
 autoimmune phenotypes",
 American Journal of Human Genetics, 76:561-571.

58. AT Lee, W Li, A Liew, C Bombardier, M Weisman, EM Massarotti, J Kent,
 F Wolfe, A Begovich, PK Gregersen (2005),
 "The PTPN22 R620W polymorphism associates with RF positive rheumatoid
 arthritis in a dose-dependent manner but not with HLA-SE status",
 Genes and Immunity, 6(2):129-133.

57. A Addo, J Le, W Li, I Aksentijevich, J Balow Jr, A Lee,
 PK Gregersen, DL Kastner, EF Remmers (2005),
 "Analysis of CARD15/NOD2 haplotypes fails to identify common
 variants associated with rheumatoid arthritis susceptibility",
 Scandinavian Journal of Rheumatology, 34(3):198-203.

56. W Li, D Holste (2004),
 "An unusual 500,000 bases long oscillation of guanine and cytosine content
 in human chromosome 21",
 Computational Biology and Chemistry, 28(5-6):393-399.

55. W Li, D Holste (2004),
 "Spectral analysis of guanine and cytosine fluctuations of mouse
 genomic DNA",
 Fluctuation and Noise Letters, 4(3):L453-L464.

54. JD Halley, AC Warden, S Sadedin, W Li (2004),
 "Rapid self-organized criticality: fractal evolution in extreme
 environments",
 Physical Review E,  70:036118.

53. HC Meng, MM Griffiths, EF Remmers, Y Kawahito, W Li, R Neisa,
 GW Cannon, RL Wilder, PS Gulko (2004),
 "Identification of two novel female-specific non-MHC loci
 regulating collagen-induced arthritis severity and chronicity,
 and evidence for epistasis",
 Arthritis & Rheumatism, 50(8):2695-2705.

52. W Li, FZ Sun, I Grosse (2004),
 "Extreme-value distribution based gene selection criteria
 for discriminant microarray data analysis using logistic regression",
 Journal of Computational Biology, 11(2-3):215-226.

51. W Li, PK Gregersen (2004)
 "Reconstructing haplotypes in pedigrees: the importance of parental
 information",
 American Journal of Medical Genetics, 124A:107-109.

50.  W Li, I Grosse (2004),
 "Comments on 'Linguistic features in eukaryotic genomes' " (letters to
 the editor),
 Complexity, 9(4):10-11.


49. A Ulgen, Z Han, W Li (2003)
 "Correlation between quantitative traits and correlation between
 corresponding LOD scores: detection of pleiotropic effects",
 BMC Genetics, 4(suppl 1):S60.

48. M Sanchez-Carbayo, N Socci, JJ Lozano, W Li, E Charytonowicz,
 T Belbin, M Preystowski, A Ortiz, G Childs, C Cordon-Cardo (2003)
 "Gene discovery in bladder cancer progression using cDNA microarrays",
 American Journal of Pathology, 163:505-516.

47. W Li, I Grosse (2003)
 "Gene selection criterion for discriminant microarray data analysis
 based on extreme value distributions",
 RECOMB2003: Proceedings of the Seventh Annual International Conference
 of Computational Molecular Biology, pages 217-223 (ACM Press).

46. W Li, JL Oliver, P Bernaola-Galvan, P Carpena (2003)
 "Isochores merit the prefix 'iso' ",
 Computational Biology and Chemistry, 27(1):5-10.
 and preprint:  http://genomebiology.com/2002/3/11/preprint/0009,

45. W Li (2002)
 "Zipf's law everywhere",
 Glottometrics, 5:14-21.

44. W Li, Y Yang (2002)
 "Zipf's law in importance of genes for cancer classification",
 Journal of Theoretical Biology, 219(4):539-551.

43. W Li (2002)
 "Are isochore sequences homogeneous?"
 Gene, 300(1-2):129-139.

42. RK Azad, JS Rao, W Li, R Ramaswamy (2002),
 "Simplifying the mosaic description of DNA sequences",
 Physical Review E, 66:031913.

41. D Jawaheer, W Li , RR Graham, W Chen, A Damle, X Xiao,
 J Monteiro, H Khalili, A Lee, R Lundsten, A Begovich,
 T Bugawan, H Erlich, JT Elder, LA Criswell, MF Seldin,
 CI Amos, TW Behrens, PK Gregersen (2002),
 "Dissecting the genetic complexity of the association between human
 leukocyte antigens and rheumatoid arthritis",
 American Journal of Human Genetics, 71:585-594.

40. Z Han, SC Heath, D Shmulewitz, W Li, SB Auerbach, ML Blundel, T Lehner,
 J Ott, M Stoffel, JM Friedman, JL Breslow (2002)
 "Candidate genes involved in cardiovascular risk factors in a family-based
 association study on the island of Kosrae, Federated States of Micronesia",
 American Journal of Medical Genetics, 110(3):234-242.

39. W Li, P Bernaola-Galvan, F Haghighi, I Grosse (2002)
 "Applications of recursive segmentation to the DNA sequence analysis",
 Computers & Chemistry (genome and informatics special issue), 26(5):491-510.

38. LJ Fang, W Li, N Chalhoub, J Feingold, J Ortenberg, J-P Thirion (2002)
 "Linkage disequilibrium  and founder effect analysis of the NF1 gene
 in French Canadians from the Quebec population",
 Annales de Genetique, 45:39-44.

37. W Li, Y Yang (2002)
 "How many genes are needed for a discriminant microarray data analysis?",
 in "Methods of Microarray Data Analysis", eds. SM Lin and KF Johnson,
 pp.137-150  (Kluwer Academic)

36. LJ Fang, N Chalhoub, W Li, J Feingold, J Ortenberg,  J-P Thirion (2001)
 "Genotyping analysis of the NF1 gene in the French Canadians from
 the Quebec population",
 American Journal of Medical Genetics, 104:189-198.

35. W Li (2001)
 "Delineating relative homogeneous G+C domains in DNA sequences",
 Gene, 276:57-72.

34. W Li, D Nyholt (2001)
 "Marker selection by Akaike information criterion and Bayesian information
 criterion",
 Genetic Epidemiology, 21(suppl 1):S272-S277.

33. D Gordon, J Hoh, SJ Finch, MA Levenstein, J Edington, W Li, J Majewski,
 J Ott (2001)
 "Two approaches for consolidating results from genome scans of complex
 traits: selection methods and scan statistics",
 Genetic Epidemiology, 21(suppl 1):S396-S342.

32. W Li (2001)
 "New stopping criteria for segmenting DNA sequences",
 Physical Review Letters, 86(25):5815-5818.

31. W Li (2001)
 "DNA segmentation as a model selection process",
 RECOMB2001: Proceedings of the Fifth Annual International Conference
 of Computational Molecular Biology, pages 204-210 (ACM Press).

30. W Li, J Reich (2000)
 "A complete enumeration and classification of two-locus disease models",
 Human Heredity, 50:334-349.

29. W Li, F Haghighi, CT Falk (1999)
 "Design of artificial neural network and its application to the
 analysis of alcoholism data",
 Genetic Epidemiology, 17(suppl 1):S223-S228.

28. W Li (1999)
 "Statistical properties of open reading frames in complete genome
 sequences",
 Computers & Chemistry (informatics and the genome issue), 23(3-4):283-301.

27. W Li, CSJ Fann, J Ott (1998)
 "Low order polynomial trends of female-to-male map distance ratios
 along human chromosomes",
 Human Heredity, 48(5):266-270.

26. W Li, G Stolvitzky, P Bernaola-Galvan, JL Oliver  (1998)
 "Compositional heterogeneity within, and uniformity between, DNA sequences
 of yeast chromosomes",
 Genome Research, 8(9):916-928.


25. JJ Higgins, I Litvan, LT Pho, W Li, LE Nee (1998)
 "Progressive supranuclear gaze palsy is in linkage disequilibrium
 with the tau and not the alpha-synuclein gene",
 Neurology, 50(1):270-273.

24.  W Li (1998)
 "Comments on 'Simplicity and complexity in gene evolution' ", (letter to
 the editor), Complexity, 3(5):10.

23.  W Li (1998)
 "Comments on 'Zipf's law and structures and evolution of natural
 languages' ", (letter to the editor),
 Complexity, 3(5):9-10.

 W Li (2003),
 "Reply to 'On words and genes' by A.A. Tsonis and P.A.Tsonis",
 (letters to the editor), Complexity, 8(5):13-14.


22. F Haghighi, W Li,  CSJ Fann (1997)
 "Affected sibpair analysis of bipolar disorder using data on chromosome 18",
 Genetic Epidemiology, 14:641-646.

21. W Li (1997)
 "The complexity of DNA: the measure of compositional heterogeneity in
 DNA sequences and measures of complexity",
 Complexity, 3(2):33-37.

20. W Li (1997)
 "Study of correlation structure in DNA sequences: a critical review",
 Computers & Chemistry,  21(4):257-272.

19. AC Walsh, W Li, DR Rosen, DA Lawrence (1996)
 "Genetic mapping of GLCLC, the human gene encoding the catalytic subunit of
 gamma-glutamylcysteine synthetase, to chromosome 6p12 and characterization
 of a polymorphic trinucleotide repeat within its 5' untranslated region",
 Cytogenetics and Cell Genetics, 75(1):14-16.

18.  W Li  (1996)
 "Comments on 'Bell Curves and Monkey Languages'" (letter to the editor),
 Complexity, 1(6):6.

17. W Li, T Marr and K Kaneko (1994)
 "Understanding statistical long-range correlations in DNA sequences",
 Physica D, 75:392-416.

16. W Li and K Kaneko (1992)
 "DNA correlations" (scientific correspondence),
 Nature, 360:635-636.

15. W Li and K Kaneko (1992)
 "Long-range correlation and partial 1/f spectrum in a non-coding
 DNA sequence",
 Europhysics Letters, 17(7):655-660. [featured in Science magazine
 (Aug 7, 1992) and Scientific Americans (Sept 1992)]

14. W Li (1992)
 "Generating non-trivial long-range correlations and 1/f spectra by
 replication and mutation",
 International Journal of Bifurcation and Chaos, 2(1):137-154.

13. W Li (1992)
 "Random texts exhibit Zipf's-law-like word frequency distribution",
 IEEE Transactions on Information Theory, 38(6):1842-1845.

12. W Li (1992)
 "Phenomenology of non-local cellular automata",
 Journal of Statistical Physics,  68(5-6):829-882.

11. W Li and M Nordahl (1992)
 "Transient behavior of cellular automata rule 110",
 Physics Letters A,  166(5-6):335-339.

10. W Li (1991)
 "Absence of 1/f spectra in Dow Jones daily average",
 International Journal of Bifurcations and Chaos, 1(3):583-597.

9. W Li (1991)
 "Expansion-modification systems: a model for spatial 1/f spectra",
 Physical Review A, 43(10):5240-5260.

8. W Li (1991)
 "On the  relationship between complexity and entropy for Markov chains
 and regular languages",
 Complex Systems, 5(4):381-399.

7. W Li (1990)
 "Mutual information functions versus correlation functions",
 Journal of Statistical Physics, 60(5-6):823-837.

6. W Li and N Packard (1990)
 "The structure of the elementary cellular automata rule space",
 Complex Systems, 4(3):281-298.

5. W Li, N Packard and C Langton (1990)
 "Transition phenomena in cellular automata rule space",
 Physica D (Nonlinearity),  45(1-3):77-94.

4. W Li (1989)
 "Spatial 1/f spectra in open dynamical systems",
 Europhysics Letters, 10(5):395-400.

3. W Li (1989)
 "Complex patterns generated by next nearest neighbors cellular automata",
 Computer & Graphics, 13(4):531-537.

2. W Li (1987)
 "Spectra of regular language and cellular automata",
 Complex Systems, 1(1):107-130.

1. W Li and P Bak (1986),
 "Fractal dimension of Cantori",
 Physical Review Letters, 57(6):655-658.



PUBLICATIONS - ABSTRACTS
------------------------

 YJ Suh, HS Lee, F Batliwalla, W Li (2006)
 Using pedigree founders only or using all pedigree members?
 -- A comparison of SNP-expression regression results
 Genetic Analysis Workshop 15,

 W Fury, F Batliwalla, PK Gregersen, W Li (2006)
 Overlapping probabilities of top ranking gene lists, hypergeometric
 distribution, and stringency of gene selection criterion
 IEEE Engineering in Medicine and Biology Society Annual Conference,
 Aug 30-Sept 3, New York, NY

 W Li, YJ Suh, J Zhang (2006)
 Does logarithm transformation of microarray data affect rank order
 of differentially expressed genes?
 IEEE Engineering in Medicine and Biology Society Annual Conference,
 Aug 30-Sept 3, New York, NY

 ZL Hu, JM Reecy, W Li (2006)
 A database for genetic analysis software,
 Plant and Animal Genome Conference, January 14-16, 2006, San Diego, CA

 F Batliwalla, C Ritchlin, W Li, X Xiao, M Brenner, T Laragione, T Shao,
 R Durham, S Kemshetti, E Schwarz, R Coe, M Kern, EC Baechler, TW Behrens,
 PK Gregersen, PS Gulko (2005),
 Microarray analyses of peripheral blood cells identifies unique gene
 expression signature that differentiates psoriatic arthritis from
 controls and from rheumatoid arthritis,
 American Congress of Rheumatology Annual Scientific Meeting, Nov 12-17,
 2005, San Diego, CA

 FM Batliwalla, EC Baechler, W Li, X Xiao, AR Damle, W Ortmann, J Novitzke,
 S Carsons, D Fischer, R Schoen, JA Molitor, E Schned, R Furie, M Kern,
 TW Behrens, PK Gregersen (2005),
 Peripheral blood gene expression profiling in rheumatoid arthritis:
 potential utility for the prediction of response to anti-TNF therapy
 American Congress of Rheumatology Annual Scientific Meeting, Nov 12-17,
 2005, San Diego, CA

 PK Gregersen, W Chen, AT Lee, MF Seldin, W Li, M Kern, EF Remmers,
 LA Criswell, DL Kastner, CI Amos (2005),
 Genome wide linkage scan of 748 affected sibling pair families with
 rheumatoid arthritis using the Illumina linkage IV set of ~5,600 SNP
 markers,
 American Congress of Rheumatology Annual Scientific Meeting, Nov 12-17,
 2005, San Diego, CA

 CC Chu, ST Reese, LO Goodwin, D Guzowski, A Chandrasekaran, C Gawel,
 W Li, PK Gregersen, XJ Yan, B Sherry, M Centola, SL Allen, KR Rai,
 N Chiorazzi (2005),
 Elevated serum interleukin-10 is not associated with promoter
 polymorphism (-1082, -819, -592) in B-cell chronic lymphocytic
 leukemia,
 International Workshop on CLL, Sept 16-18, 2005, Brooklyn NY.

 E Remmers, J Balow Jr, W Li, I Aksentijevich, A Lee, A Damle, W Chen, C Amos,
 P Gregersen, D Kastner (2004),
 Linkage disequilibrium structure and association analysis of candidate genes
 located within the rheumatoid arthritis susceptibility region on chromosome 18q,
 The Keystone symposium "Human Genome Sequence Variation and the Inherited
 Basis of Common Disease", Jan 8-13, 2004, Breckenridge, CO.

 E Remmers, J Balow Jr, W Li, I Aksentijevich, A Lee, A Damle, W Chen,
 C Amos, P Gregersen, D Kastner (2003),
 Possible association of a 14 kb haplotype block from the receptor
 mactivator of NF-kappa B (RANK) gene with susceptibility to rheumatoid
 arthritis
 American Journal of Human Genetics, ?. page ?

 D Jawaheer, W Li, R Graham, W Chen, A Damle, X Xiao, J Monteiro,
 H Khalili, A Lee, R Lundsten, A Begovich, T Bugawan, H Erlich, JT Elder,
 LA Criswell, MF Seldin, CI Amos, T Behrens, PK Gregersen (2002),
 Dissecting the genetic complexity of the HLA association with rheumatoid
 arthritis,
 American Congress of Rheumatology Annual Scientific Meeting,

 W Li, Y Yang, J Edington, F Haghighi (2001)
 Determination of the number of genes required for a discriminant
 microarray data analysis, Integrating Genome Sequence, Sequence
 Variation and Gene Expression (Cold Spring Harbor Lab)

 F Haghighi, WN Grundy, W Li (2001)
 An alternative method for computational detection of CpG island
 Genome Sequencing & Biology (Cold Spring Harbor Lab)

 W Li, A Sherriff, X Liu (2000)
 Assessing risk factors of human complex diseases by Akaike and
 Bayesian information criteria (AIC and BIC)
 American Journal of Human Genetics, s67. page 222.

 W Li (2000)
 A set of bioinformatics web resources
 Genome Sequencing & Biology (Cold Spring Harbor Lab), page 160.

 D Kessler, W Li (2000)
 Segmentation analysis of yeast telomere sequences
 Genome Sequencing & Biology (Cold Spring Harbor Lab), page 142.

 W Li, F Haghighi (1999)
 Perl as a tool for linkage analysis.
 American Journal of Human Genetics, s65, page A260.

 F Haghighi, P Banerjee, W Li (1999)
 Application of artificial neural networks in whole-genome
 analysis of complex diseases.
 Genome Sequencing & Biology (Cold Spring Harbor Lab), page 75.

 W Li (1998)
 An exact calculation of the probability of identity-by-descent in
 two-locus models using an extension of the Li-Sacks' method.
 American Journal of Human Genetics, s63, page A297.

 JL Oliver, W Li (1998)
 Quantitative analysis of compositional heterogeneity in long
 DNA sequences: the two-level segmentation test
 Genome Mapping, Sequencing & Biology (Cold Spring Harbor Lab), page 163.

 W Li (1997)
 A complete listing and classification of two-locus two-allele
 fully-penetrant disease model.
 American Journal of Human Genetics, s61, page A204.

 W Li, VFG Haghighi, TC Matise, J Ott (1996)
 Using web browsers as the graphical user interface for linkage analysis.
 American Journal of Human Genetics, s59, page A307.

 W Li, CSJ Fann, J Ott (1995)
 Positional difference of male-female genetic distances in all autosomal
 chromosomes using the computer program TREND.
 American Journal of Human Genetics, s57, page A197

 W Li, TG Marr (1994)
 Theoretical studies of size distributions of inherited and
 identical-by-descent segments in pedigrees.
 Genome Mapping & Sequencing (Cold Spring Harbor Lab).


UNPUBLISHED PAPERS
------------------

 W Li (1999)
 Large-Scale Patterns in DNA Texts
 (unused manuscript prepared for Scientific American)

 JL Oliver, W Li (1998)
 Evaluating compositional homogeneity in DNA sequences: a two-level
 segmentation test

 W Li, M Zhang and T Marr (1994)
 The statistical distribution of the length of DNA segments that are
 identical-by-descent using a single crossover model,
 (Cold Spring Harbor Lab preprint)

 W Li (1989)
 Mutual information functions of natural language texts,
 (Santa Fe Institute working paper 89-008, November 1989).


PUBLICATIONS - UNREFEREED BOOK CHAPTERS
---------------------------------------

 W Li (1995)
 Pattern 1170 in "Pattern Book: Fractals, Art, and Nature" by C. Pickover
 World Scientific, 1995)

 W Li (1992, 1997)
 Non-local cellular automata, in 1991 Lectures in Complex Systems, Santa Fe
 Institute Studies in the Sciences of Complexity, Vol IV, eds.
 L. Nadel and D. Stein, pp. 317-327 (Addison-Wesley).  Reprinted in
 "Pattern Formation in the Physical and Biological Sciences" eds. D.L. Stein,
 L. Nadel, and F. Nijhout (Addison-Wesley, 1997).

 W Li (1991)
 Expansion-modification systems and spatial 1/f spectra,
 in  Proceedings of the 1991 International Conference on Noise in
 Physical Systems and 1/f Fluctuations, eds.  T. Musha, S. Sato, and
 M. Yamamoto, pp. 519-522 (Ohmsha).

 W Li (1989)
 Mutual information functions versus correlation functions in
 binary sequences,
 in  Measures of Complexity and Chaos, eds.  N.B. Abraham, A.M. Albano, A.
 Passamante, and P.E. Rapp (NATO ASI Series, Series B: Physics Vol. 208),
 249-252 (Plenum).


ONLINE RESOURCES
----------------

 http://www.nslij-genetics.org/microarray/
 Publications on microarray data analysis (1999-now).
 Selected as a "webpick of the day" by the BioMedNet Magazine, HMS
 Beagle, on April 20, 2000. Recommended in "Handbook of Bioinformatics"
 (Shanghai Science and Technology Press, 2000. in Chinese)
 Mirrored at the Centre of Bioinformatics at Beijing University
 (http://www.cbi.pku.edu.cn/mirror/microarray/microarray.html)

 http://www.nslij-genetics.org/gene/
 bibliography on computational gene recognition (1995-now):
 A collection of publications for more than 21 years (1982-now)
 on computational gene recognition. Recommended by several books and
 review articles, including  the 1997 Review Issue of Human Medical
 Genetics and "Genetics Databases" edited by Bishop (Academic Press, 1999).
 Mirrored at the Centre of Bioinformatics at Beijing University
 (http://www.cbi.pku.edu.cn/mirror/gene/gene.html)

 http://www.nslij-genetics.org/duplication/
 Publications on gene and genome duplication (2001-now)

 http://www.nslij-genetics.org/dnacorr/
 A bibliography on features, patterns, correlations in DNA and protein
 sequences (1995-now):
 A collection of publications for the last 11 years (1992-now) on
 correlation structures of DNA texts.

 http://www.nslij-genetics.org/seq/
 A list of completely sequenced genome (1998-now)

 http://www.nslij-genetics.org/bioinfotraining/
 A list of bioinformatics courses (1999-now):
 Mirrored at University of Nebraska Medical Center
 (http://molbio.unmc.edu/Other-tools/rock-page.html) and
 Centre of Bioinformatics at Beijing University
 (http://www.cbi.pku.edu.cn/binf_course)


 http://linkage.rockefeller.edu/
 Web resource of genetic linkage analysis (1995-now):
 comprehensive information on genetic linkage analysis. Selected as a
 "best of comp.infosystems.web.announce" in October 1996. Listed in
 (among others): Genome Mapping: A Practical Approach (Dear, ed. IRL
 Press, 1997), Approaches to Gene Mapping in Complex Human Diseases
 (Haines, Pericak-Vance, eds. Wiley-Liss, 1998), Genetics of Mental
 Disorder (Faraone, Tsuang, Tsuang, eds. Guilford Press, 1999).

 http://www.nslij-genetics.org/soft/
 Mirrored at http://linkage.rockefeller.edu/soft/
 An alphabetic list of genetic analysis software (1995-now):
 Comprehensive collection of more than 230 computer software on
 linkage analysis, marker mapping, and pedigree drawing.
 Recommended in December'96 issue of Trends in Genetics.

 http://www.nslij-genetics.org/wli/1fnoise/
 A bibliography on 1/f spectra (1995-now):
 For the first time, a collection of publications on 1/f noise in
 diverse fields is brought together online. Recommended in the
 "Numerical Analysis and Associated Fields Resource Guide"
 (sci.math.num-analysis newsgroup).

 http://www.nslij-genetics.org/wli/zipf/
 A page on Zipf's law (1997-now):
 Linked by, among others, ABC News online (science section, 1999).

 http://linkage.rockefeller.edu/soft/perl/
 Perl as a tool for linkage analysis (1999):
 Collection of Perl scripts for various tasks in linkage analysis,
 including automating genome-wide linkage analysis, handling data
 for complex diseases, etc.

 http://www.nslij-genetics.org/cnv/
 A bibliography of copy number variation (2008-now)

 http://www.nslij-genetics.org/ld/
 A bibliography on linkage disequilibrium analysis (1995-now).

 http://www.nslij-genetics.org/apbib/
 A bibliography on absolute pitch (2008-now)

 http://linkage.rockefeller.edu/bib/ibd/
 A bibliography on allele-sharing linkage analysis (1995-2001).

 http://linkage.rockefeller.edu/bib/algorithm/
 A bibliography on algorithms in linkage analysis (1995-2001).

 http://linkage.rockefeller.edu/bib/vc/
 A bibliography on variance components analysis of human
 quantitative traits (1999).

 http://linkage.rockefeller.edu/gui/webpreplink.html
 web-preplink (1996):
 A CGI/perl program for online preparing input file for the
 LINKAGE programs.